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Role of tumour necrosis factor in the induction of nitric oxide synthase in a rat model of endotoxin shock.

1. This study investigates the role of tumour necrosis factor (TNF) in the induction of nitric oxide synthase (NOS) by bacterial endotoxin (lipopolysaccharide; LPS) in a rat model of endotoxin shock. 2. In anaesthetized rats, pretreatment with a monoclonal antibody for TNF (TNFab; 20 mg kg-1, s.c.,...

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Bibliographische Detailangaben
Hauptverfasser: Thiemermann, C., Wu, C. C., Szabó, C., Perretti, M., Vane, J. R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1993
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2176026/
https://ncbi.nlm.nih.gov/pubmed/7693276
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