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Induction by endotoxin of nitric oxide synthase in the rat mesentery: lack of effect on action of vasoconstrictors.

1. Male Sprague-Dawley or Wistar rats were injected with bacterial lipopolysaccharide (LPS; 5 mg kg-1, i.p.) and killed after 1, 3, 6, 15, and 24 h. The brains, mesenteries, spleens, lungs, livers, kidneys, hearts, aortae and diaphragms were removed and frozen immediately. Control rats were injected...

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Main Authors: Mitchell, J. A., Kohlhaas, K. L., Sorrentino, R., Warner, T. D., Murad, F., Vane, J. R.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1993
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175581/
https://ncbi.nlm.nih.gov/pubmed/7684306
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