Co-induction of nitric oxide synthase and cyclo-oxygenase: interactions between nitric oxide and prostanoids.

1. Lipopolysaccharide (LPS) co-induces nitric oxide synthase (iNOS) and cyclo-oxygenase (COX-2) in J774.2 macrophages. Here we have used LPS-activated J774.2 macrophages to investigate the effects of exogenous or endogenous nitric oxide (NO) on COX-2 in both intact and broken cell preparations. NOS...

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Autores principales: Swierkosz, T A, Mitchell, J A, Warner, T D, Botting, R M, Vane, J R
Formato: Artigo
Lenguaje:Inglês
Publicado: 1995
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1510271/
https://ncbi.nlm.nih.gov/pubmed/7541688
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