Pharmacological profile of valsartan: a potent, orally active, nonpeptide antagonist of the angiotensin II AT1-receptor subtype.

1. The pharmacological profile of valsartan, (S)-N-valeryl-N-([2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl)-vali ne, a potent, highly selective, and orally active antagonist at the angiotensin II (AII) AT1-receptor, was studied in vitro and in vivo. 2. Valsartan competed with [125I]-AII at its s...

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Main Authors: Criscione, L., de Gasparo, M., Bühlmayer, P., Whitebread, S., Ramjoué, H. P., Wood, J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 1993
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175903/
https://ncbi.nlm.nih.gov/pubmed/8242249
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