Capacitative Calcium Entry Deficits and Elevated Luminal Calcium Content in Mutant Presenilin-1 Knockin Mice

Dysregulation of calcium signaling has been causally implicated in brain aging and Alzheimer's disease. Mutations in the presenilin genes (PS1, PS2), the leading cause of autosomal dominant familial Alzheimer's disease (FAD), cause highly specific alterations in intracellular calcium signa...

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書誌詳細
主要な著者: Leissring, Malcolm A., Akbari, Yama, Fanger, Christopher M., Cahalan, Michael D., Mattson, Mark P., LaFerla, Frank M.
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2000
主題:
Brief Report
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174559/
https://ncbi.nlm.nih.gov/pubmed/10811821
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