P(0) Glycoprotein Overexpression Causes Congenital Hypomyelination of Peripheral Nerves

We show that normal peripheral nerve myelination depends on strict dosage of the most abundantly expressed myelin gene, myelin protein zero (Mpz). Transgenic mice containing extra copies of Mpz manifested a dose-dependent, dysmyelinating neuropathy, ranging from transient perinatal hypomyelination t...

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Detaylı Bibliyografya
Asıl Yazarlar: Wrabetz, Lawrence, Feltri, Maria Laura, Quattrini, Angelo, Imperiale, Daniele, Previtali, Stefano, D'Antonio, Maurizio, Martini, Rudolf, Yin, Xinghua, Trapp, Bruce D., Zhou, Lei, Chiu, Shing-Yan, Messing, Albee
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2000
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Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174542/
https://ncbi.nlm.nih.gov/pubmed/10704451
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