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Formation of a Tap/NXF1 Homotypic Complex Is Mediated through the Amino-Terminal Domain of Tap and Enhances Interaction with Nucleoporins

Nuclear export of mRNAs is mediated by the Tap/Nxt1 pathway. Tap moves its RNA cargo through the nuclear pore complex by direct interaction with nucleoporin phenylalanine-glycine repeats. This interaction is strengthened by the formation of a Tap/Nxt1 heterodimer. We now present evidence that Tap ca...

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Hlavní autoři: Matzat, Leah H., Berberoglu, Stephen, Lévesque, Lyne
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174195/
https://ncbi.nlm.nih.gov/pubmed/17978099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-03-0255
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