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Mutations in Tap Uncouple RNA Export Activity from Translocation through the Nuclear Pore Complex

Interactions between transport receptors and phenylalanine-glycine (FG) repeats on nucleoporins drive the translocation of receptor-cargo complexes through nuclear pores. Tap, a transport receptor that mediates nuclear export of cellular mRNAs, contains a UBA-like and NTF2-like folds that can associ...

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Autors principals: Lévesque, Lyne, Bor, Yeou-Cherng, Matzat, Leah H., Jin, Li, Berberoglu, Stephen, Rekosh, David, Hammarskjöld, Marie-Louise, Paschal, Bryce M.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356601/
https://ncbi.nlm.nih.gov/pubmed/16314397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-07-0634
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