Prediction of structural domains of TAP reveals details of its interaction with p15 and nucleoporins

Vertebrate TAP is a nuclear mRNA export factor homologous to yeast Mex67p. The middle domain of TAP binds directly to p15, a protein related to the nuclear transport factor 2 (NTF2), whereas its C-terminal domain interacts with various nucleoporins, the components of the nuclear pore complex (NPC)....

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Bibliographic Details
Main Authors: Suyama, Mikita, Doerks, Tobias, Braun, Isabelle C., Sattler, Michael, Izaurralde, Elisa, Bork, Peer
Format: Artigo
Language:Inglês
Published: Oxford University Press 2000
Subjects:
Scientific Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083685/
https://ncbi.nlm.nih.gov/pubmed/11256625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvd009
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