The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates.

Eitemau Tebyg

• TAP binds to the constitutive transport element (CTE) through a novel RNA-binding motif that is sufficient to promote CTE-dependent RNA export from the nucleus.
  gan: Braun, I C, et al.
  Cyhoeddwyd: (1999)
• Dbp5, a DEAD-box protein required for mRNA export, is recruited to the cytoplasmic fibrils of nuclear pore complex via a conserved interaction with CAN/Nup159p.
  gan: Schmitt, C, et al.
  Cyhoeddwyd: (1999)
• TAP (NXF1) Belongs to a Multigene Family of Putative RNA Export Factors with a Conserved Modular Architecture
  gan: Herold, Andrea, et al.
  Cyhoeddwyd: (2000)
• REF, an evolutionary conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export.
  gan: Stutz, F, et al.
  Cyhoeddwyd: (2000)
• Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex.
  gan: Kutay, U, et al.
  Cyhoeddwyd: (1997)