The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates.

Messenger RNAs are exported from the nucleus as large ribonucleoprotein complexes (mRNPs). To date, proteins implicated in this process include TAP/Mex67p and RAE1/Gle2p and are distinct from the nuclear transport receptors of the beta-related, Ran-binding protein family. Mex67p is essential for mRN...

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Detalhes bibliográficos
Main Authors: Bachi, A, Braun, I C, Rodrigues, J P, Panté, N, Ribbeck, K, von Kobbe, C, Kutay, U, Wilm, M, Görlich, D, Carmo-Fonseca, M, Izaurralde, E
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369901/
https://ncbi.nlm.nih.gov/pubmed/10668806
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