Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow axonal transport

The COOH-terminal tail of mammalian neurofilament heavy subunit (NF-H), the largest neurofilament subunit, contains 44-51 lysine–serine–proline repeats that are nearly stoichiometrically phosphorylated after assembly into neurofilaments in axons. Phosphorylation of these repeats has been implicated...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Rao, Mala V., Garcia, Michael L., Miyazaki, Yukio, Gotow, Takahiro, Yuan, Aidong, Mattina, Salvatore, Ward, Chris M., Calcutt, Nigel A., Uchiyama, Yasuo, Nixon, Ralph A., Cleveland, Don W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2002
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174004/
https://ncbi.nlm.nih.gov/pubmed/12186852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200202037
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk