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The neurofilament middle molecular mass subunit carboxyl-terminal tail domains is essential for the radial growth and cytoskeletal architecture of axons but not for regulating neurofilament transport rate

The phosphorylated carboxyl-terminal “tail” domains of the neurofilament (NF) subunits, NF heavy (NF-H) and NF medium (NF-M) subunits, have been proposed to regulate axon radial growth, neurofilament spacing, and neurofilament transport rate, but direct in vivo evidence is lacking. Because deletion...

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Detalhes bibliográficos
Main Authors: Rao, Mala V., Campbell, Jabbar, Yuan, Aidong, Kumar, Asok, Gotow, Takahiro, Uchiyama, Yasuo, Nixon, Ralph A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173612/
https://ncbi.nlm.nih.gov/pubmed/14662746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200308076
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