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Recognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 γ–σ1 and AP-3 δ–σ3 hemicomplexes

The sorting of transmembrane proteins to endosomes and lysosomes is mediated by signals present in the cytosolic tails of the proteins. A subset of these signals conform to the [DE]XXXL[LI] consensus motif and mediate sorting via interactions with heterotetrameric adaptor protein (AP) complexes. How...

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Bibliografiske detaljer
Main Authors: Janvier, Katy, Kato, Yukio, Boehm, Markus, Rose, Jeremy R., Martina, José A., Kim, Bong-Yoon, Venkatesan, Sundararajan, Bonifacino, Juan S.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173715/
https://ncbi.nlm.nih.gov/pubmed/14691137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200307157
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