Differential recognition of a dileucine-based sorting signal by AP-1 and AP-3 reveals a requirement for both BLOC-1 and AP-3 in delivery of OCA2 to melanosomes

Cell types that generate unique lysosome-related organelles (LROs), such as melanosomes in melanocytes, populate nascent LROs with cargoes that are diverted from endosomes. Cargo sorting toward melanosomes correlates with binding via cytoplasmically exposed sorting signals to either heterotetrameric...

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Hauptverfasser: Sitaram, Anand, Dennis, Megan K., Chaudhuri, Rittik, De Jesus-Rojas, Wilfredo, Tenza, Danièle, Setty, Subba Rao Gangi, Wood, Christopher S., Sviderskaya, Elena V., Bennett, Dorothy C., Raposo, Graça, Bonifacino, Juan S., Marks, Michael S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2012
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418312/
https://ncbi.nlm.nih.gov/pubmed/22718909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-06-0509
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