BLOC-2 targets recycling endosomal tubules to melanosomes for cargo delivery

Hermansky–Pudlak syndrome (HPS) is a group of disorders characterized by the malformation of lysosome-related organelles, such as pigment cell melanosomes. Three of nine characterized HPS subtypes result from mutations in subunits of BLOC-2, a protein complex with no known molecular function. In thi...

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Udgivet i:J Cell Biol
Main Authors: Dennis, Megan K., Mantegazza, Adriana R., Snir, Olivia L., Tenza, Danièle, Acosta-Ruiz, Amanda, Delevoye, Cédric, Zorger, Richard, Sitaram, Anand, de Jesus-Rojas, Wilfredo, Ravichandran, Keerthana, Rux, John, Sviderskaya, Elena V., Bennett, Dorothy C., Raposo, Graça, Marks, Michael S., Setty, Subba Rao Gangi
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2015
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442807/
https://ncbi.nlm.nih.gov/pubmed/26008744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201410026
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