Polarized sorting of the copper transporter ATP7B in neurons mediated by recognition of a dileucine signal by AP-1

Neurons are highly polarized cells having distinct somatodendritic and axonal domains. Here we report that polarized sorting of the Cu(2+) transporter ATP7B and the vesicle-SNARE VAMP4 to the somatodendritic domain of rat hippocampal neurons is mediated by recognition of dileucine-based signals in t...

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Bibliographic Details
Published in:Mol Biol Cell
Main Authors: Jain, Shweta, Farías, Ginny G., Bonifacino, Juan S.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2015
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294670/
https://ncbi.nlm.nih.gov/pubmed/25378584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-07-1177
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