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The γ/σ1 and α/σ2 Hemicomplexes of Clathrin Adaptors AP-1 and AP-2 Harbor the Dileucine Recognition Site

The clathrin adaptors AP-1 and AP-2 bind cargo proteins via two types of motifs: tyrosine-based Yxxφ and dileucine-based [DE]XXXL[LI]. Although it is well established that Yxxφ motifs bind to the μ subunits of AP-1 or AP-2, dileucine motifs have been reported to bind to either the μ or β subunits of...

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Hlavní autoři: Doray, Balraj, Lee, Intaek, Knisely, Jane, Bu, Guojun, Kornfeld, Stuart
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855031/
https://ncbi.nlm.nih.gov/pubmed/17360967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-01-0012
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