Basolateral sorting of chloride channel 2 is mediated by interactions between a dileucine motif and the clathrin adaptor AP-1

In spite of the many key cellular functions of chloride channels, the mechanisms that mediate their subcellular localization are largely unknown. ClC-2 is a ubiquitous chloride channel usually localized to the basolateral domain of epithelia that regulates cell volume, ion transport, and acid–base b...

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Veröffentlicht in:Mol Biol Cell
Hauptverfasser: de la Fuente-Ortega, Erwin, Gravotta, Diego, Bay, Andres Perez, Benedicto, Ignacio, Carvajal-Gonzalez, Jose Maria, Lehmann, Guillermo L., Lagos, Carlos F., Rodríguez-Boulan, Enrique
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2015
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4436783/
https://ncbi.nlm.nih.gov/pubmed/25739457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-01-0047
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