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Proteolytic release of the carboxy-terminal fragment of proHB-EGF causes nuclear export of PLZF
Cleavage of membrane-anchored heparin-binding EGF-like growth factor (proHB-EGF) via metalloprotease activation yields amino- and carboxy-terminal regions (HB-EGF and HB-EGF-C, respectively), with HB-EGF widely recognized as a key element of epidermal growth factor receptor transactivation in G prot...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Rockefeller University Press
2003
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2173632/ https://ncbi.nlm.nih.gov/pubmed/14597771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200303017 |
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