Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain

Diacylglycerol (DAG) lipase activity is required for axonal growth during development and for retrograde synaptic signaling at mature synapses. This enzyme synthesizes the endocannabinoid 2-arachidonoyl-glycerol (2-AG), and the CB1 cannabinoid receptor is also required for the above responses. We no...

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Xehetasun bibliografikoak
Egile Nagusiak: Bisogno, Tiziana, Howell, Fiona, Williams, Gareth, Minassi, Alberto, Cascio, Maria Grazia, Ligresti, Alessia, Matias, Isabel, Schiano-Moriello, Aniello, Paul, Praveen, Williams, Emma-Jane, Gangadharan, Uma, Hobbs, Carl, Di Marzo, Vincenzo, Doherty, Patrick
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2003
Gaiak:
Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173631/
https://ncbi.nlm.nih.gov/pubmed/14610053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200305129
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