Palmitoylethanolamide counteracts substance P-induced mast cell activation in vitro by stimulating diacylglycerol lipase activity

BACKGROUND: Palmitoylethanolamide (PEA) is a pleiotropic endogenous lipid mediator currently used as a “dietary food for special medical purposes” against neuropathic pain and neuro-inflammatory conditions. Several mechanisms underlie PEA actions, among which the “entourage” effect, consisting of PE...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Petrosino, Stefania, Schiano Moriello, Aniello, Verde, Roberta, Allarà, Marco, Imperatore, Roberta, Ligresti, Alessia, Mahmoud, Ali Mokhtar, Peritore, Alessio Filippo, Iannotti, Fabio Arturo, Di Marzo, Vincenzo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933707/
https://ncbi.nlm.nih.gov/pubmed/31878942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1671-5
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