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The diacylglycerol lipases: structure, regulation and roles in and beyond endocannabinoid signalling
The diacylglycerol lipases (DAGLs) hydrolyse diacylglycerol to generate 2-arachidonoylglycerol (2-AG), the most abundant ligand for the CB(1) and CB(2) cannabinoid receptors in the body. DAGL-dependent endocannabinoid signalling regulates axonal growth and guidance during development, and is require...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Royal Society
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3481529/ https://ncbi.nlm.nih.gov/pubmed/23108545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2011.0387 |
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