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A novel Apaf-1–independent putative caspase-2 activation complex
CVaspase activation is a key event in apoptosis execution. In stress-induced apoptosis, the mitochondrial pathway of caspase activation is believed to be of central importance. In this pathway, cytochrome c released from mitochondria facilitates the formation of an Apaf-1 apoptosome that recruits an...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2173397/ https://ncbi.nlm.nih.gov/pubmed/12460989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200209004 |
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