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Bcl-2–regulated apoptosis and cytochrome c release can occur independently of both caspase-2 and caspase-9

Apoptosis in response to developmental cues and stress stimuli is mediated by caspases that are regulated by the Bcl-2 protein family. Although caspases 2 and 9 have each been proposed as the apical caspase in that pathway, neither is indispensable for the apoptosis of leukocytes or fibroblasts. To...

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Detalhes bibliográficos
Main Authors: Marsden, Vanessa S., Ekert, Paul G., Van Delft, Mark, Vaux, David L., Adams, Jerry M., Strasser, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172407/
https://ncbi.nlm.nih.gov/pubmed/15210727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200312030
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