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The role of cytochrome c in caspase activation in Drosophila melanogaster cells

The release of cytochrome c from mitochondria is necessary for the formation of the Apaf-1 apoptosome and subsequent activation of caspase-9 in mammalian cells. However, the role of cytochrome c in caspase activation in Drosophila cells is not well understood. We demonstrate here that cytochrome c r...

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Detalhes bibliográficos
Main Authors: Dorstyn, Loretta, Read, Stuart, Cakouros, Dimitrios, Huh, Jun R., Hay, Bruce A., Kumar, Sharad
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173478/
https://ncbi.nlm.nih.gov/pubmed/11901173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200111107
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