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Intact satellite cells lead to remarkable protection against Smn gene defect in differentiated skeletal muscle
Deletion of murine Smn exon 7, the most frequent mutation found in spinal muscular atrophy, has been directed to either both satellite cells, the muscle progenitor cells and fused myotubes, or fused myotubes only. When satellite cells were mutated, mutant mice develop severe myopathic process, progr...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172949/ https://ncbi.nlm.nih.gov/pubmed/12743106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200210117 |
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