Interferons and IRF-1 induce expression of the survival motor neuron (SMN) genes.

BACKGROUND: Spinal muscular atrophy (SMA) is a common recessive disorder, characterized by degeneration of motor neurons of the spinal cord. Deletions, conversions, or mutations of the survival motor neuron gene (SMN) are responsible for SMA. A highly homologous centromeric copy of the SMN gene (SMN...

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Main Authors: Baron-Delage, S., Abadie, A., Echaniz-Laguna, A., Melki, J., Beretta, L.
Format: Artigo
Sprog:Inglês
Udgivet: 2000
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949924/
https://ncbi.nlm.nih.gov/pubmed/11147573
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