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Intact satellite cells lead to remarkable protection against Smn gene defect in differentiated skeletal muscle

Deletion of murine Smn exon 7, the most frequent mutation found in spinal muscular atrophy, has been directed to either both satellite cells, the muscle progenitor cells and fused myotubes, or fused myotubes only. When satellite cells were mutated, mutant mice develop severe myopathic process, progr...

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書誌詳細
主要な著者: Nicole, Sophie, Desforges, Benedicte, Millet, Gaelle, Lesbordes, Jeanne, Cifuentes-Diaz, Carmen, Vertes, Dora, Cao, My Linh, De Backer, Fabienne, Languille, Laetitia, Roblot, Natacha, Joshi, Vandana, Gillis, Jean-Marie, Melki, Judith
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2003
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172949/
https://ncbi.nlm.nih.gov/pubmed/12743106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200210117
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