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Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow
Chemokines arrest circulating lymphocytes within the vasculature through the rapid up-regulation of leukocyte integrin adhesive activity, promoting subsequent lymphocyte transmigration. However, the key regulatory molecules regulating this process have remained elusive. Here, we demonstrate that Rap...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172897/ https://ncbi.nlm.nih.gov/pubmed/12707305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200301133 |
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