The M-Ras-RA-GEF-2-Rap1 Pathway Mediates Tumor Necrosis Factor-α–dependent Regulation of Integrin Activation in Splenocytes

The Rap1 small GTPase has been implicated in regulation of integrin-mediated leukocyte adhesion downstream of various chemokines and cytokines in many aspects of inflammatory and immune responses. However, the mechanism for Rap1 regulation in the adhesion signaling remains unclear. RA-GEF-2 is a mem...

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Detalhes bibliográficos
Main Authors: Yoshikawa, Yoko, Satoh, Takaya, Tamura, Takashi, Wei, Ping, Bilasy, Shymaa E., Edamatsu, Hironori, Aiba, Atsu, Katagiri, Koko, Kinashi, Tatsuo, Nakao, Kazuki, Kataoka, Tohru
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949361/
https://ncbi.nlm.nih.gov/pubmed/17538012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-03-0250
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