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Rap1 Functions as a Key Regulator of T-Cell and Antigen-Presenting Cell Interactions and Modulates T-Cell Responses

Activation of T cells by antigen requires adhesive interactions with antigen-presenting cells (APC) in which leukocyte function-associated antigen 1 (LFA-1) and intercellular adhesion molecules (ICAMs) are important. However, it is not well understood what signaling molecules regulate this process a...

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Detalhes bibliográficos
Main Authors: Katagiri, Koko, Hattori, Masakazu, Minato, Nagahiro, Kinashi, Tatsuo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC134636/
https://ncbi.nlm.nih.gov/pubmed/11809793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.4.1001-1015.2002
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