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Critical roles for the COOH-terminal NITY and RGT sequences of the integrin β(3) cytoplasmic domain in inside-out and outside-in signaling

Bidirectional signaling of integrin α(IIb)β(3) requires the β(3) cytoplasmic domain. To determine the sequence in the β(3) cytoplasmic domain that is critical to integrin signaling, cell lines were established that coexpress the platelet receptor for von Willebrand factor (vWF), glycoprotein Ib-IX,...

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Auteurs principaux: Xi, Xiaodong, Bodnar, Richard J., Li, Zhenyu, Lam, Stephen C.-T., Du, Xiaoping
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172800/
https://ncbi.nlm.nih.gov/pubmed/12860973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200303120
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