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Critical roles for the COOH-terminal NITY and RGT sequences of the integrin β(3) cytoplasmic domain in inside-out and outside-in signaling

Bidirectional signaling of integrin α(IIb)β(3) requires the β(3) cytoplasmic domain. To determine the sequence in the β(3) cytoplasmic domain that is critical to integrin signaling, cell lines were established that coexpress the platelet receptor for von Willebrand factor (vWF), glycoprotein Ib-IX,...

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Detalhes bibliográficos
Main Authors: Xi, Xiaodong, Bodnar, Richard J., Li, Zhenyu, Lam, Stephen C.-T., Du, Xiaoping
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172800/
https://ncbi.nlm.nih.gov/pubmed/12860973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200303120
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