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A clathrin/dynamin- and mannose-6-phosphate receptor–independent pathway for granzyme B–induced cell death

The 280-kD cation-independent mannose-6-phosphate receptor (MPR) has been shown to play a role in endocytic uptake of granzyme B, since target cells overexpressing MPR have an increased sensitivity to granzyme B–mediated apoptosis. On this basis, it has been proposed that cells lacking MPR are poor...

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Bibliografische gegevens
Hoofdauteurs: Trapani, Joseph A., Sutton, Vivien R., Thia, Kevin Y.T., Li, Yu Qin, Froelich, Christopher J., Jans, David A., Sandrin, Mauro S., Browne, Kylie A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2003
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172645/
https://ncbi.nlm.nih.gov/pubmed/12538642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200210150
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