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A novel role for granzymes in anti-tumor immunity

The cytotoxic properties of granzymes are well established, though recent publications suggest additional roles for granzymes in immunity. We demonstrated that granzymes can act as regulators of cross-presentation by dendritic cells by inducing critical “eat-me” signals on the dying tumor cell, resu...

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Bibliografiske detaljer
Main Authors: Hoves, Sabine, Sutton, Vivien R., Trapani, Joseph A.
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377003/
https://ncbi.nlm.nih.gov/pubmed/22720248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.1.2.18102
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