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Processive capping by formin suggests a force-driven mechanism of actin polymerization

Regulation of actin polymerization is essential for cell functioning. Here, we predict a novel phenomenon—the force-driven polymerization of actin filaments mediated by proteins of the formin family. Formins localize to the barbed ends of actin filaments, but, in contrast to the standard capping pro...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Kozlov, Michael M., Bershadsky, Alexander D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172604/
https://ncbi.nlm.nih.gov/pubmed/15596547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200410017
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