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A novel mechanism of actin filament processive capping by formin: solution of the rotation paradox

The FH2 domains of formin family proteins act as processive cappers of actin filaments. Previously suggested stair-stepping mechanisms of processive capping imply that a formin cap rotates persistently in one direction with respect to the filament. This challenges the formin-mediated mechanism of in...

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Autori principali: Shemesh, Tom, Otomo, Takanori, Rosen, Michael K., Bershadsky, Alexander D., Kozlov, Michael M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171452/
https://ncbi.nlm.nih.gov/pubmed/16157699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200504156
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