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Processive capping by formin suggests a force-driven mechanism of actin polymerization

Regulation of actin polymerization is essential for cell functioning. Here, we predict a novel phenomenon—the force-driven polymerization of actin filaments mediated by proteins of the formin family. Formins localize to the barbed ends of actin filaments, but, in contrast to the standard capping pro...

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Detalhes bibliográficos
Main Authors: Kozlov, Michael M., Bershadsky, Alexander D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172604/
https://ncbi.nlm.nih.gov/pubmed/15596547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200410017
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