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Ubiquitin charging of human class III ubiquitin-conjugating enzymes triggers their nuclear import
Ubiquitin is a small polypeptide that is conjugated to proteins and commonly serves as a degradation signal. The attachment of ubiquitin (Ub) to a substrate proceeds through a multi-enzyme cascade involving an activating enzyme (E1), a conjugating enzyme (E2), and a protein ligase (E3). We previousl...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172591/ https://ncbi.nlm.nih.gov/pubmed/15545318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200406001 |
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