Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis

The biological antagonism between Notch and Numb controls the proliferative/differentiative balance in development and homeostasis. Although altered Notch signaling has been linked to human diseases, including cancer, evidence for a substantial involvement of Notch in human tumors has remained elusi...

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Hlavní autoři: Pece, Salvatore, Serresi, Michela, Santolini, Elisa, Capra, Maria, Hulleman, Esther, Galimberti, Viviana, Zurrida, Stefano, Maisonneuve, Patrick, Viale, Giuseppe, Di Fiore, Pier Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2004
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172557/
https://ncbi.nlm.nih.gov/pubmed/15492044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200406140
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