HIV-1 Nef disrupts MHC-I trafficking by recruiting AP-1 to the MHC-I cytoplasmic tail

To avoid immune recognition by cytotoxic T lymphocytes (CTLs), human immunodeficiency virus (HIV)-1 Nef disrupts the transport of major histocompatibility complex class I molecules (MHC-I) to the cell surface in HIV-infected T cells. However, the mechanism by which Nef does this is unknown. We repor...

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Autores principales: Roeth, Jeremiah F., Williams, Maya, Kasper, Matthew R., Filzen, Tracey M., Collins, Kathleen L.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2004
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172469/
https://ncbi.nlm.nih.gov/pubmed/15569716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200407031
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