Mathematical modeling reveals threshold mechanism in CD95-induced apoptosis

Mathematical modeling is required for understanding the complex behavior of large signal transduction networks. Previous attempts to model signal transduction pathways were often limited to small systems or based on qualitative data only. Here, we developed a mathematical modeling framework for unde...

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Main Authors: Bentele, M., Lavrik, I., Ulrich, M., Stößer, S., Heermann, D.W., Kalthoff, H., Krammer, P.H., Eils, R.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2004
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172102/
https://ncbi.nlm.nih.gov/pubmed/15364960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200404158
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