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Mathematical modeling reveals threshold mechanism in CD95-induced apoptosis

Mathematical modeling is required for understanding the complex behavior of large signal transduction networks. Previous attempts to model signal transduction pathways were often limited to small systems or based on qualitative data only. Here, we developed a mathematical modeling framework for unde...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bentele, M., Lavrik, I., Ulrich, M., Stößer, S., Heermann, D.W., Kalthoff, H., Krammer, P.H., Eils, R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172102/
https://ncbi.nlm.nih.gov/pubmed/15364960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200404158
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