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Mathematical modeling reveals threshold mechanism in CD95-induced apoptosis

Mathematical modeling is required for understanding the complex behavior of large signal transduction networks. Previous attempts to model signal transduction pathways were often limited to small systems or based on qualitative data only. Here, we developed a mathematical modeling framework for unde...

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Detalhes bibliográficos
Main Authors: Bentele, M., Lavrik, I., Ulrich, M., Stößer, S., Heermann, D.W., Kalthoff, H., Krammer, P.H., Eils, R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172102/
https://ncbi.nlm.nih.gov/pubmed/15364960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200404158
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