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Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality control
Misfolded proteins retained in the endoplasmic reticulum (ER) are degraded by the ER-associated degradation pathway. The mechanisms used to sort them from correctly folded proteins remain unclear. Analysis of substrates with defined folded and misfolded domains has revealed a system of sequential ch...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The Rockefeller University Press
2004
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172089/ https://ncbi.nlm.nih.gov/pubmed/15078901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200309132 |
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