Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway

Presenilin 1 (PS1) interacts with telencephalin (TLN) and the amyloid precursor protein via their transmembrane domain (Annaert, W.G., C. Esselens, V. Baert, C. Boeve, G. Snellings, P. Cupers, K. Craessaerts, and B. De Strooper. 2001. Neuron. 32:579–589). Here, we demonstrate that TLN is not a subst...

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Autori principali: Esselens, Cary, Oorschot, Viola, Baert, Veerle, Raemaekers, Tim, Spittaels, Kurt, Serneels, Lutgarde, Zheng, Hui, Saftig, Paul, De Strooper, Bart, Klumperman, Judith, Annaert, Wim
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2004
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172014/
https://ncbi.nlm.nih.gov/pubmed/15452145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200406060
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