Bicarbonate-responsive “soluble” adenylyl cyclase defines a nuclear cAMP microdomain

Bicarbonate-responsive “soluble” adenylyl cyclase resides, in part, inside the mammalian cell nucleus where it stimulates the activity of nuclear protein kinase A to phosphorylate the cAMP response element binding protein (CREB). The existence of this complete and functional, nuclear-localized cAMP...

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Main Authors: Zippin, Jonathan H., Farrell, Jeanne, Huron, David, Kamenetsky, Margarita, Hess, Kenneth C., Fischman, Donald A., Levin, Lonny R., Buck, Jochen
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2004
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172001/
https://ncbi.nlm.nih.gov/pubmed/14769862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200311119
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