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Soluble Adenylyl Cyclase Mediates Nerve Growth Factor-induced Activation of Rap1

Nerve growth factor (NGF) and the ubiquitous second messenger cyclic AMP(cAMP) are both implicated in neuronal differentiation. Multiple studies indicate that NGF signals to at least a subset of its targets via cAMP, but the link between NGF and cAMP has remained elusive. Here, we have described the...

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Detalhes bibliográficos
Main Authors: Stessin, Alexander M., Zippin, Jonathan H., Kamenetsky, Margarita, Hess, Kenneth C., Buck, Jochen, Levin, Lonny R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092367/
https://ncbi.nlm.nih.gov/pubmed/16627466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M603500200
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