Soluble adenylyl cyclase is required for netrin-1 signaling in nerve growth cones

Growth cones at the tips of nascent and regenerating axons direct axon elongation. Netrin-1, a secreted molecule that promotes axon outgrowth and regulates axon pathfinding, elevates cyclic AMP (cAMP) levels in growth cones and regulates growth cone morphology and axonal outgrowth. These morphologic...

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Bibliografiske detaljer
Main Authors: Wu, Karen Y, Zippin, Jonathan H, Huron, David R, Kamenetsky, Margarita, Hengst, Ulrich, Buck, Jochen, Levin, Lonny R, Jaffrey, Samie R
Format: Artigo
Sprog:Inglês
Udgivet: 2006
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081654/
https://ncbi.nlm.nih.gov/pubmed/16964251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1767
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