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Soluble adenylyl cyclase is required for netrin-1 signaling in nerve growth cones
Growth cones at the tips of nascent and regenerating axons direct axon elongation. Netrin-1, a secreted molecule that promotes axon outgrowth and regulates axon pathfinding, elevates cyclic AMP (cAMP) levels in growth cones and regulates growth cone morphology and axonal outgrowth. These morphologic...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3081654/ https://ncbi.nlm.nih.gov/pubmed/16964251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1767 |
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